| 2022 | Mi-Ock Baek, Hye-jeong Cho, Do Sik Min, Cheol Soo Choi* & Mee-Sup Yoon*. Self-transducible LRS-UNE-L peptide enhances muscle regeneration Journal of Cachexia, Sarcopenia and Muscle. 13(2):1277-1288 |
| 2022 | Kim Y, Park S, Lee J, Jang J, Jung J, Koh JH, Choi CS, Wolfe RR, Kim IY. Essential Amino Acid-Enriched Diet Alleviates Dexamethasone-Induced Loss of Muscle Mass and Function through Stimulation of Myofibrillar Protein Synthesis and Improves Glucose Metabolism in Mice. Metabolites. 12(1):84 |
| 2022 | Um JH, Park SY, Hur JH, Lee HY, Jeong KH, Cho Y, Lee SH, Yoon SM, Choe S, Choi CS. Bone morphogenic protein 9 is a novel thermogenic hepatokine secreted in response to cold exposure. Metabolism. 129:155139 |
| 2022 | Shin-Hae Lee, Shi-Young Park, Cheol Soo Choi. Insulin resistance: from mechanisms to therapeutic strategies. Diabetes Metab J. 46(1):15-37 |
| 2021 | Kalu K. Asanka Sanjeewa, Kalahe H. N. M. Herath , Hye-Won Yang, Cheol Soo Choi*, and You-Jin Jeon*. Anti-Inflammatory Mechanisms of Fucoidans to Treat Inflammatory Diseases: A Review. Mar. Drugs 19(12):678 |
| 2021 | Kim A, Koo JH, Jin X, Kim W, Park SY, Park S, Rhee EP, Choi CS, Kim SG. Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes. J Cachexia Sarcopenia Muscle. 12(6):1669-1689 |
| 2021 | Jang J, Park S, Kim Y, Jung J, Lee J, Chang Y, Lee SP, Park BC, Wolfe RR, Choi CS*, Kim IY*. Myostatin Inhibition-Induced Increase in Muscle Mass and Strength Was Amplified by Resistance Exercise Training, and Dietary Essential Amino Acids Improved Muscle Quality in Mice. Nutrients. 13(5):1508 |
| 2021 | Kim J, Kim SH, Kang H, Lee S, Park SY, Cho Y, Lim YM, Ahn JW, Kim YH, Chung S, Choi CS, Jang YJ, Park HS, Heo Y, Kim KH, Lee MS. TFEB-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response. Nat Metab. 3(3):410-427 |
| 2021 | Kang GM, Min SH, Lee CH, Kim JY, Lim HS, Choi MJ, Jung SB, Park JW, Kim S, Park CB, Dugu H, Choi JH, Jang WH, Park SE, Cho YM, Kim JG, Kim KG, Choi CS, Kim YB, Lee C, Shong M, Kim MS. Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism. Cell Metab. 33(2):334-349 |
| 2021 | Mok J, Park TS, Kim S, Kim D, Choi CS, Park J. Prokineticin receptor 1 ameliorates insulin resistance in skeletal muscle. FASEB J. 35(2):e21179 |
| 2021 | Choi SJ, Kim SM, Kim YS, Kwon OS, Shin SK, Kim KK, Lee K, Park IB, Choi CS, Chung DH, Jung J, Paek M, Lee DH. Magnetic Resonance-Based Assessments Better Capture Pathophysiologic Profiles and Progression in Nonalcoholic Fatty Liver Disease. Diabetes Metab J. 45(5):739-752 |
| 2020 | Kim IY, Park S, Kim Y, Chang Y, Choi CS, Suh SH, Wolfe RR.In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench.. Endocrinol Metab. 35(4):733-749 |
| 2020 | Won-Chul Lee, N.G. Gurudatt, Deog-Su Park, Kwang Bok Kim, Cheol Soo Choi*, Yoon-Bo Shim*. Microneedle array sensor for monitoring glucose in single cell using glucose oxidase-bonded polyterthiophene coated on AuZn oxide layer. Sensors and Actuators B: Chemical 320: 128416 |
| 2020 | Kim J, Kim H, Noh SH, Jang DG, Park SY, Min D, Kim H, Kweon HS, Kim H, Aum S, Seo S, Choi CS, Kim H, Kim JW, Moon SJ, Gee HY, Lee MG. Grasp55-/- mice display impaired fat absorption and resistance to high-fat diet-induced obesity. Nat Commun. 11(1):1418 |
| 2020 | Park H, Jang HR, Park S, Kim Y, Lee H, Choi CS. The essential role of fructose-1,6-bisphosphatase 2 enzyme in thermal homeostasis upon cold stress. 52(3):485-496. Exp Mol Med 52(3):485-496 |
| 2020 | Shin JH, Lee G, Jeong MG, Kim HK, Won HY, Choi Y, Lee JH, Nam M, Choi CS, Hwang GS, Hwang ES. Transcriptional coactivator with PDZ-binding motif suppresses the expression of steroidogenic enzymes by nuclear receptor 4 A1 in Leydig cells. FASEB J. 34(4):5332-5347 |
| 2020 | Jung YS, Kim YH, Radhakrishnan K, Kim J, Kim DK, Lee JH, Oh H, Lee IK, Kim W, Cho SJ, Choi CS, Dooley S, Egan JM, Lee CH, Choi HS. An inverse agonist of estrogen-related receptor γ regulates 2-arachidonoylglycerol synthesis by modulating diacylglycerol lipase expression in alcohol-intoxicated mice. Arch Toxicol. 94(2):427-438 |
| 2020 | Shin SK, Kim KO, Kim SH, Kwon OS, Choi CS, Jeong SH, Kim YS, Kim JH, Chung MH. Exogenous 8-hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1-NADPH oxidase signaling. J Gastroenterol Hepatol. 35(6):1078-1087 |
| 2019 | Kim TH, Koo JH, Heo MJ, Han CY, Kim YI, Park SY, Cho IJ, Lee CH, Choi CS, Lee JW, Kim W, Cho JY, Kim SG, Overproduction of inter-α-trypsin inhibitor heavy chain 1 after loss of Gα13 in liver exacerbates systemic insulin resistance in mice. Sci Transl Med. 11(513) |
| 2019 | Kim TH, Lee K, Park IB, Choi CS, Ahn TH, Lee DH. The effects of DPP4 inhibitors on the levels of plasma catecholamines and their metabolites in patients with type 2 diabetes. Diabetes Res Clin Pract. 156:107832 |
| 2019 | Lee K, Park IB, Yu SH, Kim SK, Kim SH, Seo DH, Hong S, Jeon JY, Kim DJ, Kim SW, Choi CS, Lee DH. Characterization of variable presentations of diabetic ketoacidosis based on blood ketone levels and major society diagnostic criteria: a new view point on the assessment of diabetic ketoacidosis. Diabetes Metab Syndr Obes. 12:1161-1171 |
| 2019 | Mozammal Hossain MD, Moon JM, Gurudatt NG, Park DS, Choi CS, Shim YB . Separation detection of hemoglobin and glycated hemoglobin fractions in blood using the electrochemical microfluidic channel with a conductive polymer composite sensor. Biosens Bioelectron. 142:111515 |
| 2019 | Hong Y, Lee JH, Jeong KW, Choi CS, Jun HS. Amelioration of muscle wasting by glucagon-like peptide-1 receptor agonist in muscle atrophy. J Cachexia Sarcopenia Muscle. 10(4):903-918 |
| 2019 | Lee WC, Kim KB, Gurudatt NG, Hussain KK, Choi CS, Park DS, Shim YB.Comparison of enzymatic and non-enzymatic glucose sensors based on hierarchical Au-Ni alloy with conductive polymer. Biosens Bioelectron. 130:48-54 |
| 2019 | Park JG, Mok JS, Han YI, Park TS, Kang KW, Choi CS, Park HD, Park J.Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan. Sci Rep. 9(1):4003 |
| 2018 | Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG. Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 128(12):5587-5602 |
| 2018 | Eun-Hui Lee, Michal Itan, Jinsun Jang, Hyeon-Jung Gu, Perri Rozenberg, Melissa Mingler, Ting Wen, Jiyoung Yoon, Shi-Young Park, Joo Young Roh, Cheol Soo Choi, Woo-Jae park, Ariel Munitz, and YunJae Jung. Eosinophils support adipocyte maturation and promote glucose tolerance in obesity. Sci Rep. 8(1):98945094 |
| 2018 | Murata K, Morino K, Ida S, Ohashi N, Lemecha M, Park SY, Ishikado A, Kume S, Choi CS, Sekine O, Ugi S, Maegawa H. Lack of O-GlcNAcylation enhances exercise-dependent glucose utilization potentially through AMP-activated protein kinase activation in skeletal muscle. Biochem Biophys Res Commun. 495(2):2098-2104 |
| 2017 | Kang JK, Kim OH, Hur J, Yu SH1, Lamichhane S, Lee JW, Ojha U, Hong JH, Lee CS, Cha JY, Lee YJ, Lm SS, Park YJ, Choi CS, Lee DH, Lee IK, Oh BC. increased intracellular Ca2+ concentrations prevent membrane localization of PH domains through the formation of Ca2+-phosphoinositides. Proc Natl Acad Sci U S A. 114(45):11926-11931 |
| 2017 | Koo JH, Kim TH1, Park SY2, Joo MS, Han CY, Choi CS, Kim SG. Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism. J Clin Invest. 127(10):3845-3860 |
| 2017 | Lee SY, Lee HY, Song JH, Jeon S, Song YJ, Lee JS, Hur JH, OH HH, Park SY, Shim SM, Yoo HJ Lee BC, Jiang XC, Choi CS*, Park TS* Adipocyte-specific deficiency of de novo sphingolipid biosynthesis leads to lipodystrophy and insulin resistance Diabetes 66(10):2596-2609 |
| 2017 | Ohashi N, Morino K, Ida S, Sekine O, Lemecha M, Kume S, Park SY, Choi CS, Ugi S, Maegawa H. Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis. Diabetes. 66(9):2351-2362 |
| 2017 | Mitochondrial-Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation. Lee HY, Lee JS, Alves T, Ladiges W, Rabinovitch PS, Jurczak MJ, Choi CS, Shulman GI, Samuel VT.Diabetes. 2017 2072-2081 |
| 2017 | Buddolla Viswanath, Cheol Soo Choi Kiyoung Lee Sanghyo Kim, Recent trends in the development of diagnostic tools for diabetes mellitus using patient saliva. Trends in Analytical Chemistry 89:60-67 |
| 2017 | Cho J, Zhang Y, Park SY, Joseph AM, Han C, Park HJ, Kalavalapalli S, Chun SK, Morgan D, Kim JS, Someya S, Mathews CE, Lee YJ, Wohlgemuth SE, Sunny NE, Lee HY, Choi CS, Shiratsuchi T, Oh SP, Terada N. Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. Nat Commun. 8:14477 |
| 2017 | Kim DM, Moon JM, Lee WC, Yoon JH, Choi CS, Shim YB. A potentiometric non-enzymatic glucose sensor using a molecularly imprinted layer bonded on a conducting polymer. Biosens Bioelectron. 91:276-283 |
| 2016 | Hur JH, Park SY, Dall'Armi C, Lee JS, Di Paolo G, Lee HY, Yoon MS, Min DS, Choi CS. Phospholipase D1 deficiency in mice causes nonalcoholic fatty liver disease via an autophagy defect. Sci Rep. 6:39170 |
| 2016 | Han SJ, Choi SE, Yi SA, Jung JG, Jung IR, Shin M, Kang S, Oh H, Kim HJ, Kim DJ, Kwon JE, Choi CS*, Lee KW*, Kang Y*. Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice. Sci Rep. 5:37468 |
| 2016 | Oh YT, Oh HH, Nguyen AK, Choi CS, Youn JH. Circulating free fatty acids inhibit food intake in an oleate-specific manner in rats. Physiol Behav. 167:194-201 |
| 2016 | Mee-Sup Yoon, Cheol Soo Choi. The role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistance. Experimental & Molecular Medicine 48(1): e201 |
| 2016 | Go Y, Jeong JY, Jeoung NH, Jeon JH, Park BY, Kang HJ, Ha CM, Choi YK, Lee SJ, Ham HJ, Kim BG, Park KG, Park SY, Lee CH, Choi CS, Park TS, Lee WN, Harris RA, Lee IK. Inhibition of pyruvate dehydrogenase kinase 2 protects against hepatic steatosis through modulation of TCA cycle anaplerosis and ketogenesis. Diabetes, Diabetes. 65(10):2876-87 |
| 2015 | Devadhasan JP, Oh H, Choi CS, Kim S. Whole blood glucose analysis based on smartphone camera module. J Biomed Opt. 20(11):117001, 2015. (IF 2.859) |
| 2015 | Oh H, Jeong KH, Han HY, Son HJ, Kim SS, Lee HJ, Kim S, Sa JH, Jun HS, Ryu JH, Choi CS. A potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, SKI2852, ameliorates metabolic syndrome in diabetic mice models. Eur J Pharmacol. 768:139-48, 2015 (IF 2.532) |
| 2015 | Shin JH, Kim IY, Kim YN, Shin SM, Roh KJ, Lee SH, Sohn M, Cho SY, Lee SH, Ko CY, Kim HS, Choi CS, Bae YS, Seong JK. Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak-/- Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure. PLoS One. 10(12):e0144478, 2015 (IF 3.234) |
| 2015 | Choi Y, Kwon Y, Kim DK, Jeon J, Jang SC, Wang T, Ban M, Kim MH, Jeon SG, Kim MS, Choi CS, Jee YK, Gho YS, Ryu SH, Kim YK. Gut microbe-derived extracellular vesicles induce insulin resistance, thereby impairing glucose metabolism in skeletal muscle. Sci Rep. 5:15878, 2015 (IF 5.578) |
| 2015 | Oh YS, Shin S, Li HY, Park EY, Lee SM, Choi CS, Lim Y, Jung HS, Jun HS. Betacellulin ameliorates hyperglycemia in obese diabetic db/db mice. J Mol Med (Berl). 93:1235-1245, 2015 (IF 5.107) |
| 2015 | Mir TA, Akhtar MH, Gurudatt NG, Kim JI, Choi CS, Shim YB. An amperometric nanobiosensor for the selective detection of K+-induced dopamine released from living cells. Biosens Bioelectron. 68:421-428, 2015 (IF 6.451) |
| 2015 | Lee YS, Kim D, Lee EK, Kim S, Choi CS, Jun HS. Sodium meta-arsenite prevents the development of autoimmune diabetes in NOD mice. Toxicol Appl Pharmacol. 284(2):254-61, 2015 (IF 3.630) |
| 2015 | Jong-Hee Hwang, Cheol Soo Choi. In vivo Magnetic Resonance Spectroscopy (MRS) for Studying Metabolic Diseases. Exp Mol Med 47:e139, 2015 |
| 2014 | Linkang Zhou, Shi-Young Park, Li Xu, Xiayu Xia, Jing Ye, Kyeong-Hoon Jeong, Jang Ho Hur, Hyunhee Oh, Yoshikazu Tamori, Cristina M. Zingaretti, Saverio Cinti, Jesús Argente, Miao Yu, Lu Su, Lizhen Wu, Shenghong Ju, Feifei Guan, Hongyuan Yang, Cheol Soo Choi*, David B. Savage*, Peng Li* Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice. Nat. Commun. 6:5949, 2015 * contributed equally (IF 10.742) |
| 2014 | Lee YS, Lee EK, Oh HH, Choi CS, Kim S, Jun HS. Sodium Meta-Arsenite Ameliorates Hyperglycemia in Obese Diabetic db/db Mice by Inhibition of Hepatic Gluconeogenesis. J Diabetes Res. 2014:961732, 2014. (IF 2.164) |
| 2014 | Shim KH1, Jeong KH2, Bae SO1, Kang MO1, Maeng EH3, Choi CS2, Kim YR4, Hulme J1, Lee EK1, Kim MK4, An SS1. Assessment of ZnO and SiO2 nanoparticle permeability through and toxicity to the blood-brain barrier using Evans blue and TEM. Int J Nanomedicine. 9 Suppl 2:225-33. eCollection 2014. (IF 4.383) |
| 2014 | Kibbey RG, Choi CS, Lee HY2, Cabrera O, Pongratz RL, Zhao X, Birkenfeld AL, Li C, Berggren PO, Stanley C, Shulman GI. Mitochondrial GTP insensitivity contributes to hypoglycemia in Hyperinsulinemia Hyperammonemia (HI/HA) by inhibiting glucagon release. Diabetes. 63(12):4218-29, 2014 (IF 8.474) |
| 2014 | Lee HY, Jeong KH, Choi CS. In-depth metabolic phenotyping of genetically engineered mouse models in obesity and diabetes. Mamm Genome. 25(9-10):508-521, 2014 (IF 2.883) |
| 2014 | Lee HY, Gattu AK, Camporez JP, Kanda S, Guigni B, Kahn M, Zhang D, Galbo T, Birkenfeld AL, Jornayvaz FR, Jurczak MJ, Choi CS, Yan Z, Williams RS, Shulman GI, Samuel VT. Muscle-specific activation of Ca2+/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice. Diabetologia. 57(6):1232-41, 2014 (IF 6.880) |
| 2014 | Lee EY, Kim YW, Oh H, Choi CS, Ahn JH, Lee BW, Kang ES, Cha BS, Lee HC. Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.Metabolism 63(6):793-9, 2014 (IF 3.096) |
| 2014 | Giménez-Cassina A*, Garcia-Haro L*, Choi CS*, Osundiji MA, Lane EA, Huang H, Yildirim MA, Szlyk B, Fisher JK, Polak K, Patton E, Wiwczar J, Godes M, Lee DH, Robertson K, Kim S, Kulkarni A, Distefano A, Samuel V, Cline G, Kim YB, Shulman GI, Danial NN. Regulation of hepatic energy metabolism and gluconeogenesis by BAD. Cell Metab. 19(2):272-84, 2014 * contributed equally (IF 14.619) |
| 2014 | Yi JS, Park JS, Ham YM, Nguyen N, Lee NR, Hong J, Kim BW, Lee H, Lee CS, Jeong BC, Kyu Song H, Cho H, Kim YK, Lee JS, Park KS, Shin H, Choi I, Lee SH, Park WJ, Park SY, Choi CS, Lin P, Karunasiri M, Tan T, Duann P, Zhu H, Ma J, Ko YG. MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling. Nat Commun. 4:2354, 2013 (IF 10.015) |
| 2013 | Moon HY, Song P, Choi CS, Ryu SH, Suh PG. Involvement of exercise-induced macrophage migration inhibitory factor in the prevention of fatty liver disease. J Endocrinol. 218(3):339-48, 2013 (IF 4.058) |
| 2013 | Kim DK, Gang GT, Ryu D, Koh M, Kim YN, Kim SS, Park J, Kim YH, Sim T, Lee IK, Choi CS, Park SB, Lee CH, Koo SH, Choi HS. Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis. Diabetes. 62(9):3093-102,2013 (IF 7.895) |
| 2013 | Park M, Wu D, Park T, Choi CS, Li R, Cheng KK, Xu A, Sweeney G. APPL1 transgenic mice are protected from high fat diet induced cardiac dysfunction. Am J Physiol Endocrinol Metab. 305(7):E795-804, 2013 (IF 4.514) |
| 2013 | Devadhasan JP, Kim S, Choi CS. CMOS image sensors as an efficient platform for glucose monitoring.Analyst. 138(19):5679-84, 2013 (IF 3.969) |
| 2013 | Löffler MG, Birkenfeld AL, Philbrick KM, Belman JP, Habtemichael EN, Booth CJ, Castorena CM, Choi CS, Jornayvaz FR, Gassaway BM, Lee HY, Cartee GD, Philbrick W, Shulman GI, Samuel VT, Bogan JS. Enhanced Fasting Glucose Turnover in Mice with Disrupted Action of TUG Protein in Skeletal Muscle. J Biol Chem. 288(28):20135-50, 2013 (IF 4.651) |
| 2013 | Kim KH, Jeong YT, Oh H, Kim S, Cho JM, Kim Y, Kim SS, Kim DH, Hur KY, Kim HK, Ko TH, Han J, Kim HL, Kim J, Back SH, Komatsu M, Chen H, Chan DC, Konishi M, Itoh1N, Choi CS* & Lee M*. Autophage deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a ‘mitokine’. Nat Medicine 19:83-93, 2013 (IF 22.462) * contributed equally |
| 2013 | Lee KM, Yang SJ, Kim YD, Choi YD, Nam JH, Choi CS, Choi HS, Park CS. Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high fat diet-induced obesity and insulin resistance in mice. Diabetes. 2013 Jan 24. (IF 8.286) |
| 2013 | Huh JY, Kim JI, Park YJ, Hwang IJ, Lee YS, Sohn JH, Lee SK, Alfadda AA, Kim SS, Choi SH, Lee DS, Park SH, Seong RH, Choi CS, Kim JB.A Novel Function of Adipocytes in Lipid Antigen Presentation to iNKT Cells. Mol Cell Biol. 33(2):328-39, 2013 (IF 7.667) |
| 2012 | Oh KJ, Park J, Kim SS, Oh H, Choi CS, Koo SH. TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver. PLoS Genet. 8(9):e1002986, 2012 (IF 8.694) |
| 2012 | Lee YS, Park MS, Choung JS, Kim SS, Oh HH, Choi CS, Ha SY, Kang Y, Kim Y, Jun HS. Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes. Diabetologia. 55(9):2456-68, 2012 (IF 6.814) |
| 2012 | Choi CS, Kim MY, Han K, Lee MS. Assessment of β-cell function in human patients. Islets 4(2):79-83, 2012 (IF 1.123) |
| 2012 | Lee SY, Kim JR, Hu Y, Khan R, Kim SJ, Bharadwaj KG, Davidson MM, Choi CS, Shin KO, Lee YM, Park WJ, Park IS, Jiang XC, Goldberg IJ, Park TS. Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction. J Biol Chem. 287(22):18429-39, 2012 (IF 4.773) |
| 2012 | Morino K, Petersen KF, Sono S, Choi CS, Samuel VT, Lin A, Gallo A, Zhao H, Kashiwagi A, Goldberg IJ, Wang H, Eckel RH, Maegawa H, Shulman GI. Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes. Diabetes. 61(4):877-87, 2012 (IF 8.286) |
| 2012 | Quan W, Kim HK, Moon EY, Kim SS, Choi CS, Komatsu M, Jeong YT, Lee MK, Kim KW, Kim MS, Lee MS. Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response. Endocrinology. 153(4):1817-26, 2012 (IF 4.459) |
| 2012 | Marimuthu M, Park C, Kim S, Choi CS. Real-time electrical measurement of L929 cellular spontaneous and synchronous oscillation. Int J Nanomedicine. 7:83-92, 2012 (IF 4.424) |
| 2012 | Liu W, Singh R, Choi CS, Hui-Young L, Keramati AR, Samuel VT, Lifton RP, Shulman GI, Mani A. LDL Receptor Related Protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure. J Biol Chem. 287(10):7213-23, 2012 (IF 4.773) |
| 2012 | Shinozaki S, Choi CS, Shimizu N, Yamada M, Kim M, Zhang T, Dong HH, Kim YB, Kaneki M. Liver-specific iNOS expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice. J Biol Chem. 286(40):34959-75, 2011 (IF 4.773) |
| 2011 | Lee HY, Birkenfeld AL, Jornayvaz FR, Jurczak MJ, Kanda S, Popov V, Frederick DW, Zhang D, Guigni B, Bharadwaj KG, Choi CS, Goldberg IJ, Park JH, Petersen KF, Samuel VT, Shulman GI. Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. Hepatology. 7(12):4109-19, 2011 (IF 11.665) |
| 2011 | Shin HJ, Park YH, Kim SU, Moon HB, Park DS, Han YH, Lee CH, Lee DS, Song IS, Lee DH, Kim M, Kim NS, Kim DG, Kim JM, Kim SK, Kim YN, Kim SS, Choi CS, Kim YB, Yu DY. Hepatitis B virus X protein regulates hepatic glucose homeostasis via activation of inducible nitric oxide synthase. J Biol Chem. 286(34):29872-29881, 2011 (IF 4.773) |
| 2011 | Ryu D, Seo WY, Yoon YS, Kim YN, Kim SS, Kim HJ, Park TS, Choi CS*, Koo SH*. Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance. Diabetes, 2011 (IF 8.505) *contributed equally |
| 2011 | Chang ZQ, Lee SY, Kim HJ, Kim JR, Kim SJ, Hong IK, Oh BC, Choi CS, Goldberg IJ, Park TS. endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2. Prostaglandins Other Lipid Mediat. 94(1-2):44-52, 2011 (IF 2.557) |
| 2011 | Jongin Hong, Karthikeyan Kandasamy, Mohana Marimuthu, Cheol Soo Choi and Sanghyo Kim. Electrical cell-substrate impedance sensing as a non-invasive tool for cancer cell study. Analyst 136(2), 237–245, 2011 (IF 4.230) |
| 2010 | Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI. Targeted expression of catalase to mitochondria prevents age- associated reductions in mitochondrial function and insulin resistance. Cell Metab. 12(6): 668-674, 2010 (IF 17.35) |
| 2010 | Choi CS, Ghoshal P, Srinivasan M, Kim S, Cline G, Patel MS. Liver-specific pyruvate dehydrogenase complex deficiency upregulates lipogenesis in adipose tissue and improves peripheral insulin sensitivity. Lipids 45(11): 987-995, 2010 (IF 2.382) |
| 2010 | Yoon YS, Lee MW, Ryu D, Kim JH, MA H, Seo WY, Kim YN, Kim SS, Lee CH, Hunter T, Choi CS, Montminy MR, Koo SH. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proc Natl Acad Sci USA, 107(41):17704-17709, 2010 (IF 9.432) |
| 2010 | Srinivasan M, Choi CS, Ghoshal P, Pliss L, Pandya JD, Hill DJ, Cline GW, Patel MS. Beta cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion. AM J Physiol Endocrinol Metab. 299(6): E910-917, 2010 |
| 2010 | Zhang D, Christianson J, Liu ZX, Tian L, Choi CS, Neschen S, Dong J, Wood PA, Shulman GI. Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency. Cell Metab. 115(5): 402-411, 2010 (IF 17.35) |
| 2010 | Lee MW, Chanda D, Yang J, Oh H, Kim SS, Yoon YS, Hong S, Park KG, Lee IK, Choi CS, Hanson RW, Choi HS, Koo SH. Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH. Cell metab. 11(4):331-3392010 (IF 17.35) |
| 2010 | Andrews ZB, Erion DM, Beiler R, Choi CS, Shulman GI, Horvath TL. Uncoupling Protein-2 Decreases the Lipogenic Actions of Gherlin. Endocrinology 151 (5):2078-2086, 2010 (IF 4.752) |
| 2010 | Won JC, Park JK, Kim YM, Koh EH, Seol S, Jeon BH, Han J, Kim JR, Park TS, Choi CS, Lee WJ, Kim MS, Lee IK, Youn JH, Lee KU. Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. Arterioscler Thromb vasc Biol. 30(2):290-7, 2010 |
| 2010 | Kandasamy K, Choi CS, Kim S. An efficient analysis of nanomaterial cytotoxicity based on bioimpedance. Nanotechnology. 21(37):375501, 2010 (IF 3.979) |
| 2009 | Estall JL, Ruas JL, Choi CS, Laznik D Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM. PGC-lalpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proc Natl Acad Sci USA, 106(52): 22510-22515, 2009 (IF 9.432) |
| 2009 | Liu L, Shi X, Choi CS, Shulman GI, Klaus K, Nari KS, Schwarts GJ, Zhang Y, Goldberg IJ, Yu YH. Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1. Diabetes 58:2516-2524, 2009 (IF 8.505) |
| 2009 | Ryu D, Oh KJ, Jo HY, Hedrick S, Kim YN, Hwang YJ, Park TS, Choi CS, Montminy M, Koo SH. TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metab. 9(2)240-251, 2009(IF 17.35) |
| 2009 | Rowe GC, Choi CS, Neff L, Horne WC, Shulman GI, Baron R. Increased energy expenditure and insulin sensitivity in the high bone mass {Delta}FosB transgenic mice. Endocrinology 150(1):135-143, 2009 (IF 4.752) |
| 2009 | Wang H, Knaub LA, Jensen DR, Jung DY, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Choi CS, Shulman GI, Kim JK, Kim JK, Friedman JE, Eckel RH. Skeletal Muscle-Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues. Diabetes 5(1): 116-124, 2009 (IF 8.398) |
| 2009 | Lee HJ, Lee YH, Park SK, KIM HJ, Lee YC, Choi CS, Park SE, Ahn CW, Cha BS, Lee KW, Kim KS, Lim SK, Lee HC. Korean red ginseng(Panaz ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushinma fatty rats. Metabolism 58(8):1170-1177, 2009 |
| 2008 | Cheol Soo Choi, Roberto Codella, Doughlas E. Befroy, Sheene Kim, Richard M. Reznick, Yu-Jin Hwang, Zhen-Xiang Liu, Hui-Young Lee, Alberto Distefano, Varman T. Samuel, Dongyan Zhang, Gary W. Cline, Christoph Handschin, Jiandie Lin, Kitt F. Petersen, Bruce M. Spiegelman and Gerald I. Shulman. Paradoxical Effects of Increased Expression of PGC-1 ‧α on Muscle Mitochondrial Function and Insulin Stimulated Muscle Glucose Metabolism. Proc Natl Acad Sci USA, 150(50): 19926-19931, 2008 (IF 9.38) |
| 2008 | Matthew P. Gillum, Xian-Man Zhang, Dongyan Zhang, Derek M. Erion, Rachel A. Jamison, Cheolsoo Choi, Jianying Dong, Marya Shanabrough, Hillary R. Duenas, David W. Frederick, Jennifer J. Hsiao, Tamas L. Horvath, Katie Carey, Pat Tso, Gary W. Cline, Gerald I. Shulman. N-acylphosphatidylethanolamine, a gut-derived circulating factor induced by fat ingestion, inhibits food intake. Cell 135(5):813-824, 2008 (IF 31.253) |
| 2008 | Cheol Soo Choi*. Josep A. Villena*, Yuhui Wang, Sheene Kim, Yu-Jin Hwang, Young-Bum Kim, Gary Cline, Gerald Ⅰ. Shulman and Hei Sook Sul. Resistance to high fat diet-induced obesity but exacerbated insulin resistance in mice overepressing Pref-1: a new model of partial lipodystrophy. Diabetes 57(12)3258-66, 2008 (IF 8.398) |
| 2008 | M. Faadiel Essop, Heidi S. Camp, Cheol Soo Choi, Saumya Sharma, Ryan M. Fryer, Glenn A. Reinhart, Patrick H. Guthrie, Assia Bentebibl, Zeiwei Gu, Gerald I. Shulman Heinrich Taegtmeyer, Salih J. Wakil and Lutfi Abu-Elheiga . Reduced Heart Size and Increased Myocardial Fuel Substrate Oxidation in ACC2 Mutant Mice. Am J Physiol Heart Circ Physiol (IF 3.724) |
| 2008 | David B Savage, Lanmin Zhai, Balasubramanian Ravikumar, Cheol Soo Choi, Johanna E Snaar, Amanda C McGuire, Sung-Eun Wou, Gemma Medina-Gomez, Sheene Kim, Cheryl B Bock, Dyann M Segvich, Antonio Vidal-Puig, Nicholas J Wareham, Gerald I Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A Pederson, Peter J Roach, Stephen O'Rahilly, and Anna A DePaoli-Roach. A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. Plos Med 5(1), 2008 (IF 13.75) |
| 2008 | Nika N Danial, Loren D Walensky, Chen-Yu Zhang, Cheol Soo Choi, Jill K Fisher, Anthony J A Molina, Sandeep Robert Datta, Kenneth L Pitter, Gregory H Bird, Jakob D Wikstrom, Jude T Deeney, Kirsten Robertson, Joel Morash, Ameya Kulkarni, Susanne Neschen, Sheene Kim, Michael E Greenberg, Barbara E Corkey, Orian S Shirihai, Gerald I Shulman, Bradford B Lowell & Stanley J Korsmeyer. Dual Role of Pro-apoptotic BAD in Insulin Secretion and β-Cell Survival. Nat Medicine 14: 144-153, 2008 (IF 25.6) |
| 2007 | Cheol Soo Choi, David Savage, Lufti Abu-Elheiga, Zhen-Xiang Liu, Sheene Kim, Ameya Kulkarni, Alberto Distefano, Yu-Jin Hwang, Richard M. Reznick, Roberto Codella, Dongyan Zhang, Gary W. Cline, Salih J. Wakil, Gerald I. Shulman. Continuous fat oxidation in Acetyl-CoA carboxylase 2 mutant mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity. Proc Natl Acad Sci USA 104(42): 16480-16485, 2007 (IF 9.681) |
| 2007 | Cheol Soo Choi, Jonathan J. Fillmore, Jason K. Kim, Zhen-Xiang Liu, Sheene Kim, Ameya Kulkarni, Alberto Distefano, Yu-Jin Hwang, Mario Kahn, Yan Chen, Chunli Yu, Irene K. Moore, Richard M. Reznick, Takamasa Higashimori, Emily F. Collier, Gerald I. Shulman. Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. J Clin Invest, 117:1995-2003, 2007 (IF 13.069) |
| 2007 | Dongyan Zhang, Zhen-Xiang Liu, Cheol Soo Choi,, , Liqun Tian,, Richard Kibbey, Jianying Dong, Gary W. Cline, Philip A. Wood, Gerald I. Shulman. Mitochondrial Dysfunction due to long-chain Acyl-CoA Dehydrogenase Deficiency Causes Hepatic Steatosis and Hepatic Insulin Resistance. PNAS. 104:17075-17080, 2007 (IF 9.6) |
| 2007 | Robert V. Farese, Mini P. Sajan, Hong Wang, Pengfei Li, Steven Mastorides, William R. Gower, Jr., Sonali Nimal, Cheol Soo Choi, Sheene Kim, Gerald I. Shulman, C. Ronald Kahn, Ursula Braun, and Michael Leitges. Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes. J Clin Invest, 117(8):2289-2301, 2007 (IF 15.8) |
| 2007 | Christoph Handschin, Cheol Soo Choi, Sherry Chin, Sheene Kim, Dan Kawamori, Amamath J. Kurpad, Nicole Neubauer, Jiang Hu, Fenfen Liu, Eleftheria Maratos-Flier, Vamsi K. Mootha, Young-Bum Kim, Rohit N. Kulkarni, Gerald I. Shulman, and Bruce M. Spiegelman. Abnormal glucose homeostasis in skeletal muscle-specific PGC-1α knockout mice through skeletal muscle-pancreatic B cell cross-talk. J Clin invest 117(11):3463-3474, 2007 (IF 15.8) |
| 2007 | Cheol Soo Choi, David B. Savage, Ameya Kulkarni, Xing Xian Yu, Zhen-Xiang Liu, Katsutaro Morino, Sheene Kim, Alberto Distefano, Varman T. Samuel, Susanne Neschen, Dongyan Zhang, Amy Wang, Xian-Man Zhang, Mario Kahn,Gary W. Cline, Sanjay K. Pandey, John G. Geisler, Sanjay Bhanot, Brett P. Monia, Gerald I. Shulman. Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance. JBC , 282(31):22678-88, 2007 (IF 5.8) |
| 2007 | Qingchun Tong, ChianPing Ye, Rory J. McCrimmon, Harveen Dhillon, Brian Choi, Melissa Kramer, Jia Yu, Zongfang Yang Lauryn Christiansen, Siobhan kowronek, Charlotte Lee, Cheol Soo Choi, Jeffrey M. Zigman, Gerald I. Shulman, Robert Sherwin, Joel K. Elmquist and Bradford B. Lowell1. Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab. 5(5):383-393, 2007 (IF 16.7) |
| 2007 | Jonathan B. Hurov, Mei huang, Lynn S. White, Cheol Soo Choi, You-Ree Cho, Hyo-Jeong Kim, Julie L. Prior, David Piwnica-Worms, Lewis C. Cantley, Jason K. Kim, Gerald I. Shulman and Helen Piwnica-Worms. Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo. PNAS, 104: 5680-5685, 2007 (IF 9.6) |
| 2007 | Qian Gao, Gabor Mezei, Yan Rao, Cheol Soo Choi, Ingo Bechmann, Csaba Leranth, Dominique Torran-Allerand, Catherine A. Priest, James L. Roberts, Xiao-Bing Gao, Charles Mobbs, Gerald I. Shulman, Sabrina Diano, and Tamas L. Horvath. Anorectic estrogen mimics leptin’s effect on the re-wiring of melanocortin cells and stat3 signaling in obese animals. Nat Medicine. 2007;13(1):89-94 (IF 25.6) |
| 2006 | Vianna CR, Huntgeburth M, Coppari R, Choi CS, Lin J, Stefan K, Barbatelli G, Tzameli I, Kim YB, Cinti S, Shulman G, Spiegelman B, Lowell BB. Hypomorhphic Mutation in PGC1 causes mitochondrial dysfunction and liver insulin resistance. Cell Metab. 2006, 4(6):453-64. (IF 16.7) |
| 2006 | Alon M. Chen, Bhawanjit K. Brar, Cheol Soo Choi, David Rousso, Joan M. Vaughan, Yael Kuperman, Shee Ne Kim, Cindy Donaldson, Sean M. Smith, Chien Li, Tim R. Nagy, Gerald I. Shulman, Kuo-Fen Lee, Wylie W. Vale. Urocortin 2 mediates glucose utilization and insulin sensitivity in skeletal muscle. PNAS, 103(44):16580-5, 2006 (IF 9.6) |
| 2006 | Wu JJ, Roth RJ, Anderson EJ, Hong E, Lee M, Choi CS, Neufer D, Shulman GI, Kim JK, Bennett AM: Mice Lacking Mitogen-Activated protein(MAP) Kinase Phosphatase-1 have Enhanced MAP Kinase Activity and Resistance to Diet-Induced Obesity. Cell Metabolism, 4(1):61-73, 2006. (IF 16.7) |
| 2006 | Cheol S. Choi*, Varman T. Samuel*, Trevor G. Phillips, Antony J. Romaneli, John G. Geisler, Sanjay Bhanot, Robert McKay, Brett Monia, John R. Shutter, Richard A. Lindberg, Gerald I. Shulman and Murielle M. Veniant: Targeting Foxo1 in mice using Antisense Oligonucleotide Improves Hepatic and Peripheral Insulin Action. Diabetes 55:2042-2050, 2006. * contributed equally (IF 7.9) |
| 2006 | Cheol S. Choi* , David B. Savage*, Varman T. Samuel, Zhen-Xiang Liu, Dongyan Zhang, Amy Wang, , Xian-Man Zhangi, Gary W. Cline, Xing Xian Yu, John G. Geisler, Sanjay Bhanot, Brett Monia, Gerald I.Shulman. Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. Journal of Clinical Investigation 116(3):817-824, 2006 * contributed equally (IF 15.8) |
| 2006 | Stefan Bilz, Varman Samuel, Katsutaro Morino, David Savage, Cheol Soo Choi and Gerald I. Shulman: Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters. Am J Physiol Endocrinol Metab 290:E716-E722, 2006 (IF 4.5) |
| 2005 | Noboru Furukawa, Pat Ongusaha, Wan Jin Jahng, Kazushi Araki, Cheol S. Choi, Hyo-Jeong Kim, Kazushi Araki, Yong Hee Lee, Kozo Kaibuchi, Barbara B Kahn, Hiroaki Masuzaki, Jason K Kim, Sam W Lee and Young-Bum Kim: Role of Rho-kinase in Regulation of Insulin Action and Glucose Homeostasis. Cell Metabolism 2:119-129, 2005 (IF 16.7) |
| 2005 | Susanne Neschen, Katsutaro Morino, Linda E. Hammond, Dongyan Zhang, Anthony J. Romanelli, Gary W. Cline, Zhen-Xiang Liu, Cheol Soo Choi, Rosalind A. Coleman, and Gerald I. Shulman : Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knock out mice. Cell Metabolism 2:55-65, 2005 (IF 16.7) |
